| 計畫名稱 |
執行期限 |
審核/修正通過日期 |
申請人 |
聯絡電話及郵件 |
|
AS-IRB-BM-23001
判別存在於種族間特有的乳癌分子印記
Identifying Subtype Specific Molecular Signatures for Breast Cancer
|
2023/01/30-2025/11/16
|
2023/01/30
|
楊振翔
Chen-Hsiang Yeang
|
02-66145631
#310
|
|
AS-IRB-BM-23003
大型人體生物資料庫的基因體研究
Biobank-centric genomic research
|
2023/08/01-2026/10/31
|
2023/03/03
|
楊欣洲
Hsin-Chou Yang
|
02-27875686
|
|
AS-IRB-BM-23004
財富衝擊對家戶消費、勞動供給及健康的影響：台灣的實證研究
The Impact of Wealth Shocks on Consumption, Labor Supply and Health: Evidence From Taiwan
|
2023/08/01-2027/07/31
|
2023/03/14
|
簡錦漢
Kamhon Kan
|
02-27822791
|
|
AS-IRB-BM-23005
以臺灣人體生物資料庫研究非酒精性脂肪肝疾病的生物標記
Developing biomarker for non-alcoholic fatty liver disease using Taiwan Biobank data
|
2023/03/20-2026/02/20
|
2023/03/20
|
胡春美
Chun-Mei Hu
|
02-27898777
|
|
AS-IRB-BM-23006
深入研究B型肝炎病毒多樣性在B型肝炎帶原且表面抗原陽性者
Deep profiling of HBV variants in HBeAg-positive chronic HBV patients from the REVEAL-HBV cohort
|
2023/04/07-2025/12/31
|
2023/04/07
|
楊懷壹
Hwai-I Yang
|
02-27871308
|
|
AS-IRB-BM-23007
探討人類白血球抗原類型與不同家塵蟎過敏原分子之關聯
The association between the HLA type and allergen molecules from the house dust mite
|
2023/04/10-2026/08/31
|
2023/04/10
|
陳煥源
Huan-Yuan Chen
|
02-26523940
|
|
AS-IRB-BM-23008
分析先天專一性T細胞在HBV感染的肝臟疾病的免疫反應
Analysis of innate-like antigen-specific T cell responses during hepatitis B virus (HBV)-associated liver diseases.
|
2023/03/31-2028/03/31
|
2023/03/27
|
鄭揚
Yang Cheng
|
02-26523966
|
|
AS-IRB-BM-23009
慢性B型肝炎感染與慢性腎臟病的風險，從病毒因子、環境因子到伺主因子C
hronic Hepatitis B Virus Infection and Risk of Chronic Kidney Disease
|
2023/04/10-2024/02/28
|
2023/04/10
|
楊懷壹
Hwai-I Yang
|
02-27871308
|
|
AS-IRB-BM-23010
專一性/廣效型之禽流感 mRNA 疫苗開發
Development of strain-specific or universal avian influenza mRNA vaccines
|
2023/04/07-2023/12/31
|
2023/04/07
|
劉玟君
Wen-Chun Liu
|
02-77505815
|
|
AS-IRB-BM-23011
探討新型源自大片段非編碼核糖核酸的運動神經元微小胜肽的功能—以肌萎縮性脊髓側索硬化症為例
Targeting ALS by a novel conserved motor neuron micropeptide derived from lncRNA
|
2024/01/01-2026/12/31
|
2023/05/03
|
陳俊安
Jun-An Chen
|
02-27880406
|
|
AS-IRB-BM-23012
以多層次整合途徑探討兒童肥胖的成因: 個人、家庭與地理環境
A multilevel integrated approach for elucidating the etiology of pediatric obesity: individual, family and environment
|
2024/01/01-2026/12/31
|
2023/04/07
|
詹大千
Ta-Chien Chan
|
02-2785-7108
#312
|
|
AS-IRB-BM-23013
利用大腸癌病患檢體及幹細胞建構之腸道類器官模式來探討新冠病毒造成腸道病徵之機制並找尋治療標的
Understanding gastrointestinal symptoms caused by SARS-CoV-2 infection and identifying therapeutic targets using colonic organoids derived from colorectal cancer patients’ specimen and crypt stem cells
|
2023/09/11-2024/12/31
|
2023/09/11
|
沈家寧
Chia-Ning Shen
|
02-27899580
#301
|
|
AS-IRB-BM-23014
選擇性血清素再吸收抑制劑(SSRIs)及抗憂鬱藥物(Anti-psychotic)與乾癬症影響之回顧性世代分析
Retrospective Cohort Analysis of Serotonin-Related drugs and Anti-psychotic drugs and Psoriasis Outcome
|
2023/04/25-2028/04/30
|
2023/04/25
|
李永凌
Yungling Lee
|
02-2652-3013
|
|
AS-IRB-BM-23015
以「神經網路-符號邏輯整合運算」技術建構「人工情感智慧」系統的探索性研究
An Exploring Study on Building Affective Artificial Intelligence by Neural-Symbolic Computing
|
2023/06/14-2024/07/31
|
2023/06/14
|
廖純中
Churn-Jung Liau
|
02-2788-3799 #1713
|
|
AS-IRB-BM-23016
台灣M2BPGi研究數據登錄計畫及M2BPGi監測肝臟纖維化的臨床應用
The registry of Taiwan M2BPGi data in clinical research
|
2023/05/15-2025/09/30
|
2023/05/15
|
楊懷壹
Hwai-I Yang
|
02-27871308
|
|
AS-IRB-BM-23017
探討腸道菌叢與宿主基因在肥胖及胰島素阻抗發生的角色與交互作用
Exploration of the roles and interactions of gut microbiota and host genetic factors in the development of obesity and insulin resistance
|
2023/08/08-2026/12/31
|
2023/08/08
|
鄔哲源
Jer-Yuarn Wu
|
02-27899075
|
|
AS-IRB-BM-23018
分析HBV相關肝臟疾病裡肝臟病毒專一性T細胞和免疫受器基因組在肝組織空間分佈的特性
Dissecting liver-resident virus-specific T cells and the spatial profiling of immunorepertoire during the progression of HBVassociated liver diseases
|
2023/08/01-2027/07/31
|
2023/06/14
|
鄭揚
Yang Cheng
|
02-26523966
|
|
AS-IRB-BM-23020
開發促腫瘤細胞吞噬的新穎性肺癌治療抗體
Development of Novel Phagocytosis Therapeutic Antibody for Lung Cancer
|
2023/08/01-2026/07/31
|
2023/05/18
|
楊泮池
Pan-Chyr Yang
|
02-27899149
|
|
AS-IRB-BM-23023
解析O 連結乙醯葡萄氨糖如何影響胰管腺癌腫瘤微環境中的免疫抑制進程發展
Elucidating how O-GlcNAcylation affects the progression of immunosuppression in the tumor microenvironment of pancreatic ductal adenocarcinoma
|
2024/01/01-2028/12/31
|
2023/06/15
|
林國儀
Kuo-I Lin
|
02-27871253
|
|
AS-IRB-BM-23024
探索紫外線治療下Aromatic Hydrocarbon Receptor影響抗原特異調節型T細胞的免疫機轉
Immune mechanism of Aromatic Hydrocarbon Receptor on antigenspecific regulatory T cells under UVB therapy
|
2023/07/24-2028/12/31
|
2023/07/24
|
李永凌
Yungling Lee
|
02-2652-3013
|
|
AS-IRB-BM-23026
分析血液和組織中SARS-CoV-2專一性記憶型T細胞針對突破性感染的長期免疫保護力
Defining long-term immune protection of peripheral and tissueresident memory SARS-CoV-2-specific T cells against repeated breakthrough infection
|
2023/10/31-2028/06/01
|
2023/10/31
|
鄭揚
Yang Cheng
|
02-26523966
|
|
AS-IRB-BM-23027
開發辨識癌細胞CD318抗原之嵌合抗原受體免疫細胞療法
Development of chimeric antigen receptor (CAR)-engineered immune cells targeting CD318-expressing cancer cells
|
2023/08/01-2026/07/31
|
2023/07/24
|
沈家寧
Chia-Ning Shen
|
02-27899580
#301
|
|
AS-IRB-BM-23028
台灣的婚育變遷
Changing Family Formation in Taiwan
|
2023/07/01-2026/06/30
|
2023/05/25
|
鄭雁馨
Yen-hsin Alice Cheng
|
02-26525154
|
|
AS-IRB-BM-23029
針對氣喘-肺阻塞重疊病人，探討吸入性藥物療效的特徵之研究
Characterization of inhaled pharmacological response in patients with asthma-COPD overlap
|
2023/06/20-2026/05/31
|
2023/06/20
|
張雅貞
Ya-Jen Chang
|
02-27899050
|
|
AS-IRB-BM-23030
探討 DAMP 調控子在拮抗發炎反應之功能與調控機制及其病理意義
The functions and mechanisms of DAMP modulators in constraining inflammation and the impact in inflammatory disorders
|
2023/08/01-2026/07/31
|
2023/05/31
|
翁瑞霞
Jui-Hsia Weng
|
02-27855696
#7040
|
|
AS-IRB-BM-23031
研究 Siglec-15 調節腫瘤微環境的分子機制
Investigating the molecular mechanism by which Siglec-15 modulates the tumor microenvironment
|
2023/08/01-2026/07/31
|
2023/05/29
|
安形高志
Takashi ANGATA
|
02-27855696
#6140
|
|
AS-IRB-BM-23032
研發流蘇石斛成分用於治療BRAF抑制藥物 vemurafenib 引起之黑色素瘤抗藥性與皮膚副作用
Research and development of therapeutic compounds from Dendrobium fimbriatum for combating BRAFi drug vemurafenib induced resistant in melanoma and cutaneous side effect
|
2023/08/01-2026/07/31
|
2023/06/05
|
徐麗芬
Lie-Fen Shyur
|
02-27872102
|
|
AS-IRB-BM-23033
解析酪氨酸去磷酸酶TCPTP/PTPN2進入細胞核並催化STAT1去磷酸化以關閉基因轉錄的分子機制
Unraveling the molecule mechanism of Importin-Beta1-mediated activation of Tcell protein tyrosine phosphatase (TCPTP/PTPN2) to regulate the nucleuslocalized substrate STAT1
|
2023/08/01-2025/07/31
|
2023/05/29
|
孟子青
Tzu-Ching Meng
|
02-27855696
#6010
|
|
AS-IRB-BM-23034
PLEKHH家族基因在哺乳動物神經系統中的作用
Function of PLEKHH family gene in mammalian nervous system
|
2023/07/31-2026/12/31
|
2023/05/30
|
程淮榮
Hwai-Jong Cheng
|
02-27899971
|
|
AS-IRB-BM-23035
⼈體細胞中氧化還原調節分⼦的動態功能學
Functional dynamics of redox regulators in human cells
|
2023/08/01-2025/08/31
|
2023/05/31
|
陳昇宏
Sheng-hong Chen
|
02-27899318
|
|
AS-IRB-BM-23036
探討NCoR1在長期記憶形成中扮演的角色及分子生物機制
Investigation of the role and molecular mechanism of NCoR1 in long-term memory formation
|
2023/08/01-2025/07/31
|
2023/06/06
|
李小媛
Eminy H.Y. Lee
|
02-27899125
|
|
AS-IRB-BM-23037
帶有Atg8修飾的膜狀結構於高基氏體品管中的功能探討
ATG8-POSITIVE STRUCTURES IN THE QUALITY CONTROL OF THE GOLGI APPARATUS
|
2023/08/01-2026/07/31
|
2023/06/01
|
楊維元
Wei-Yuan Yang
|
02-27855696
|
|
AS-IRB-BM-23038
本子計畫：探討心肌細胞中半乳糖凝集素在氧化壓力下之角色
群體計畫名稱：內在醣：突破細胞內醣質與醣結合蛋白的動態平衡作用
Exploring the roles of intracellular Galectins in cardiomyocytes response to oxidative stress
Glycoscience on the Inside: Unravelling the Role of Intracellular Glycans and Glycan Binding Proteins
|
2023/06/14-2024/12/31
|
2023/06/14
*2023/09/28
|
孟子青
Tzu-Ching Meng
|
02-27855696
#6010
|
|
AS-IRB-BM-23039
以新型漸凍症模式小鼠和誘導式潛能幹細胞開發治療ALS的藥物
Use a newly established ALS mouse model and iPSCs to develop therapeutic avenues in ALS
|
2024/01/01-2026/12/31
|
2023/09/01
|
陳俊安
Jun-An Chen
|
02-27880406
|
|
AS-IRB-BM-23040
總計畫＿全面揭示KRAS基因突變的癌症進展模型，以確定潛在的合併療法
子計畫#1＿KRAS 突變引起的體外形態變化和體內轉移能力的成像和追踪
子計畫#2_ KRAS 突變模型中的免疫逃避和浸潤缺失
子計畫#3_ KRAS 突變模型中脂質生物合成、膽固醇產生及其相關代謝事件
Comprehensively revealing cancer progression models of genetically altered KRAS
to identify potential combination therapies
Subproject#1_Imaging and tracking of morphological changes in vitro and metastatic capacity in vivo caused by KRAS mutations
Subproject#2_Impaired immune evasion and infiltration in the KRAS mutant model. Subproject#3_Lipid biosynthesis, cholesterol production, and their associated metabolic events in the KRAS mutant model
|
2024/01/01-2024/12/31
|
2023/08/08
|
蕭宏昇
Michael Hsiao
|
02-27871243
|
|
AS-IRB-BM-23041
非酒精性脂肪肝相關多基因風險評分與慢性B型肝炎患者其肝臟及肝臟外疾病罹病與死亡之風險分析：一個以社區為基礎的世代研究
NAFLD Related Polygenic Risk Score and Risk of Hepatic and Extrahepatic Morbidity and Mortality in Chronic Hepatitis B: A Community-Based Follow-up Study
|
2024/01/01-2024/12/31
|
2023/08/10
*2023/12/27
|
楊懷壹
Hwai-I Yang
|
02-27871308
|
|
AS-IRB-BM-23042
建立合成式Bietti 結晶性角膜視網膜營養不良之眼類器官模型
Synthetic eye organoid-based disease modeling of Bietti crystalline corneoretinal dystrophy
|
2024/01/30-2026/12/31
|
2024/01/30
|
郭紘志
Hung-Chih Kuo
|
02-27899580 #201
|
|
AS-IRB-BM-23044
開發以菌相篩檢大腸直腸癌之檢測服務平台
Developing a Service Platform for Colorectal Cancer Screening based on Gut Microbiota Profiling
|
2024/01/01-2033/12/31
|
2023/09/25
|
孟子青
Tzu-Ching Meng
|
02-27855696
#6010
|
|
AS-IRB-BM-23045
分析年輕和年老慢性Ｂ型肝炎病患在經過藥物治療後免疫反應和ＨＢＶ專一性T細胞之差異
Analysis of immune cell landscape and the HBV-specific T cell responses upon drug intervention in young versus old chronic hepatitis B infected patients
|
2024/01/01-2026/12/31
|
2023/10/11
|
鄭揚
Yang Cheng
|
02-26523966
|
|
AS-IRB-BM-23047
開發可增進 cGAS/STING 反應之標記物引導免疫療法
Development of marker-guided immunotherapy enhancing cGAS/STING response
|
2024/01/01-2028/12/31
|
2023/07/26
|
李家偉
Chia-Wei Li
|
02-26523912
|
|
AS-IRB-BM-23048
利用臺灣人體生物資料庫中基因體共祖片段及多體學資訊探索疾病遺傳機制
Using genomic identical-by-descent segments and multi-omics in Taiwan Biobank to investigate disease genetic mechanisms
|
2024/09/11-2033/12/31
|
2023/09/11
|
陳弘昕
Hung-Hsin Chen
|
02-2652-3033
|
|
AS-IRB-BM-23049
剖析卵巢透明細胞癌 (OCCC) 轉移的分子異質性－代謝重整對於卵巢亮細胞癌(OCCC) 轉移趨性之影響
Dissecting the molecular heterogeneity in the metastasis of ovarian clear cell carcinoma (OCCC)---The metabolic reprogramming of metastatic organotropism of OCCC
|
2023/08/04-2025/07/31
|
2023/08/04
|
黃雯華
Wendy Hwang-Verslues
|
02-27871246
|
|
AS-IRB-BM-23051
核心時鐘基因BMAL2在卵巢亮細胞癌之功能及其潛在治療用途
Function of core clock gene BMAL2 in ovarian clear cell carcinoma and its potential therapeutic usage
|
2024/01/01-2025/12/31
|
2023/08/10
*2024/01/09
|
黃雯華
Wendy Hwang-Verslues
|
02-27871246
|
|
AS-IRB-BM-23053
剖析卵巢透明細胞癌 (OCCC) 轉移的分子異質性－代謝重整對於卵巢亮細胞癌(OCCC) 轉移趨性之影響
Dissecting the molecular heterogeneity in the metastasis of ovarian clear cell carcinoma (OCCC)---The metabolic reprogramming of metastatic organotropism of OCCC
|
2024/01/01-2025/12/01
|
2023/08/23
|
凌嘉鴻
Steven Lin
|
02-2785-5696 #5030
|
|
AS-IRB-BM-23055
利用台灣人體生物資料庫研究慢性B型肝炎病毒感染的遺傳結構
Investigating the genetic architecture of chronic hepatitis B virus infection in the Taiwan biobank
|
2023/11/01-2024/10/31
|
2023/10/31
|
楊懷壹
Hwai-I Yang
|
02-27871308
|
|
AS-IRB-BM-23056
利用衛生福利部衛生福利資料科學中心之資料檢視表現型編碼系統之準確性、盛行率與相關共病
Evaluating the PheCode system's accuracy, prevalence, and comorbidity with Taiwan's National Health Insurance Research Database
|
2023/09/21-2033/08/31
|
2023/09/21
|
陳弘昕
Hung-Hsin Chen
|
02-26523033
|
|
AS-IRB-BM-23057
背景音樂與閱讀理解歷程的神經處理機制
The neural mechanism of background music and reading comprehension.
|
2023/09/26-2025/07/31
|
2023/09/26
|
李佳穎
Chia-Ying Lee
|
02-2652-5031
|
|
AS-IRB-BM-23058
台灣漢族人群慢性疾病之多層次風險評估：以中央研究院台灣人體資料庫為基礎的全面分析
Exploring the Multifactorial Determinants of Chronic Diseases in the Taiwanese Han Population: A Comprehensive Analysis Using the Taiwan Biobank
|
2024/10/11-2026/09/30
|
2023/10/11
|
李家偉
Chia-Wei Li
|
02-26523912
|
|
AS-IRB-BM-23059
全面生活型態重塑之肥胖線上介入研究
Total lifestyle reconstruction for body weight control and maintenance：an on-line randomized controlled trial
|
2024/1/12-2026/12/31
|
2024/01/12
|
潘文涵
Wen-Harn Pan
|
02-2789-9121
|
|
AS-IRB-BM-23060
利用轉錄因子轉換人類體細胞為視網膜前驅細胞
Transformation of human somatic cells into retinal precursors using transcription factors
|
2023/11/14-2029/11/30
|
2023/11/14
|
呂仁
Jean Lu
|
02-27899581 #601
|
|
AS-IRB-BM-23061
鑑定神經退化疾病病人組織中TDP-43蛋白堆積物的形態和檢測腦脊髓液中TDP-43蛋白含量
Identification of the morphology of TDP-43 protein aggregates in the tissues, and quantification of TDP-43 protein levels in cerebrospinal fluid of neurodegenerative disease patients
|
2023/12/26-2028/12/01
|
2023/12/26
|
陳韻如
Yun-Ru Chen
|
02-27871275
|
|
AS-IRB-BM-23063
生理訊號與元宇宙互動之研究及實驗
Research and accessing the interaction between bio-signal and Metaverse
|
2024/01/01-2026/07/31
|
2023/11/24
|
王有德
Yu Te Wang
|
02-27872389
|
|
AS-IRB-BM-23064
利用新穎果凍細胞技術刺激抗病毒T細胞的增生與加速抗原表位的鑑定
Unbiased expansion and assessment of antiviral T cell by cellular taxidermy for functional viral epitope identification
|
2024/03/01-2025/12/31
|
2023/11/30
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胡哲銘
Che-Ming Jack Hu
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02-26523089
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AS-IRB-BM-23065
剖析卵巢透明細胞癌 (OCCC) 轉移的分子異質性－代謝重整對於卵巢亮細胞癌(OCCC) 轉移趨性之影響
Dissecting the molecular heterogeneity in the metastasis of ovarian clear cell carcinoma (OCCC)---The metabolic reprogramming of metastatic organotropism of OCCC
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2024/08/01-2027/07/31
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2023/11/17
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凌嘉鴻
Steven Lin
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02-2785-5696 #5030
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AS-IRB-BM-23066
臺灣人口身高預測研究
Research on Prediction of Population Height in Taiwan
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2024/01/09-2027/01/31
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2024/01/09
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陳建勳
Chien-Hsiun Chen
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02-27824066
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AS-IRB-BM-23067
利用臺灣人體生物資料庫檢體建立健康人的代謝分布圖譜以幫助胰臟癌診斷
Establishing Metabolic Profiles of Healthy Individuals from the Taiwan Human Biobank for Pancreatic Cancer Diagnosis Support
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2024/01/09-2024/12/31
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2024/01/09
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胡春美
Chun-Mei Hu
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02-27898777
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AS-IRB-BM-23069
探討c-kit在嗜中性球性氣喘中對第三型先天性淋巴細胞的調控
c-Kit signaling modulates group 3 innate lymphoid cell function in neutrophilic asthma
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2024/08/01-2027/07/31
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2024/01/16
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張雅貞
Ya-Jen Chang
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02-27899050
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AS-IRB-BM-23070
邁向精準醫療：透過非監督式聚類在複雜疾病中發現與驗證內類型
Towards Precision Medicine: Endotypes Discovery and Validation through Unsupervised Clustering in Complex Diseases (EnDeaVoUr-Pro)
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2024/08/01-2025/07/31
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2024/01/09
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范盛娟
Cathy SJ Fann
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02-27899144
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AS-IRB-BM-23071
藉由抑制唾液酸轉移酶ST6GAL1消除冠狀病毒和流感病毒感染的風險
Inhibition of ST6GAL1 abrogates the risk of coronavirus and influenza virus infection
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2024/01/01-2028/12/31
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2023/12/26
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李家偉
Chia-Wei Li
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02-26523912
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AS-IRB-BM-23072
人類癌症之定錨基因-生物標記基因研究:生物資訊分析與驗證
Anchor-Biomarker Genes for Cancer: Bioinformatic Discovery and Validation
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2024/08/01-2027/07/31
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2024/01/17
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林文昌
Wen-chang Lin
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02-27899148
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AS-IRB-BM-23073
中心體蛋白STIL參與ALK激酶誘發腫瘤形成機轉
The role of centrosomal protein STIL in ALK-induced oncogenesis
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2024/08/01-2027/07/31
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2024/01/03
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唐堂
Tang K. Tang
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02-26523901
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AS-IRB-BM-23074
染色體5q33.3區域高血脂相關風險位點的遺傳與功能分析
Genetic and Functional Analysis to Explore a Hyperlipidemia-Related Risk Locus in 5q33.3
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2024/08/01-2026/07/31
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2024/01/09
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沈志陽
Chen-Yang Shen
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02-27893695
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AS-IRB-BM-23075
探討基因遺傳變異多型性做為預測乳癌免疫治療成效的可行性
Investigating the feasibility of predicting breast cancer response to immunotherapy by genetic variants
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2024/08/01-2027/07/31
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2024/01/10
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沈志陽
Chen-Yang Shen
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02-27893695
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AS-IRB-BM-23076
上皮細胞粘著分子(EpCAM)於腫瘤致癌機轉及調控免疫抑制之功能探討
The functional roles of EpCAM in regulating tumorigenesis and immune suppressive tumor microenvironment
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2024/08/01-2027/07/31
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2023/12/29
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吳漢忠
Han-Chung Wu
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02-27899528
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AS-IRB-BM-23079
鑑定分析調節體脂肪的聚醣磺基轉移酶的生化特徵
Biochemical characterization of a glycan sulfotransferase that regulates body fat
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2024/08/01-2027/07/31
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2023/12/29
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安形高志
Takashi ANGATA
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02-27855696
#6140
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